CD69 Monoclonal Antibody (FN50), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD69
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
Gene Symbols
CD69
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
CD69
Clone
FN50
Applications
Flow Cytometry
Conjugate
PerCP-eFluor 710
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q07108
Gene ID (Entrez)
969
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Also called AIM or activation inducer molecule, CD69 is a gp28/34 disulfide bonded homodimer with a Mr of 60kDa under non-reducing conditions
- CD69 contains one or two N linked oligosacaride
- The CD69 molecule is also present on activated platelets
- In normal peripheral blood a variable percentage of cells express the CD69 antigen
- It is involved in lymphocyte signal transduction
- CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions
- CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets
- In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction
- Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation
- Furthermore, the protein may act to transmit signals in natural killer cells and platelets
- Alternative splicing results in multiple transcript variants of CD69
- Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.