7092386
αβ T-Cell Receptor Mouse anti-Rat, FITC, Clone: R73, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
αβ T-Cell Receptor
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
R73
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Target Species
Rat
Immunogen
Rat T blasts and rat erythrocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The R73 antibody reacts with the αβ T-cell Receptor (TCR) found on most peripheral T lymphocytes, intestinal intraepithelial lymphocytes, and thymocytes
- It does not react with γδ TCR-bearing cells
- Cross-linked R73 mAb induces T-cell differentiation and activation
- In vivo treatment with mAb R73 can suppress immune function of peripheral αβ TCR-expressing T cells, and reduce the severity of experimental autoimmune, transplant rejection, and graft-versus-host responses.