7092395
CD106 Mouse anti-Human, PE, Clone: 51-10C9, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD106
Applications
Flow Cytometry
Conjugate
PE
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
VCAM-1; Vascular cell adhesion protein 1; INCAM-100; L1CAM
Clone
51-10C9
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 51-10C9 monoclonal antibody specifically binds to CD106
- CD106 is a 100-110 kDa type I transmembrane sialoglycoprotrein that is also known as Vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110
- CD106 is expressed at high levels on the surface of cytokine-stimulated endothelium, and at minimal levels on unstimulated endothelium
- VCAM-1 serves as a ligand for the leukocyte integrins α4β1 (CD49d/CD29 complex; VLA-4) and α4β7 (LPAM-1)
- The 51-10C9 monoclonal antibody inhibits the in vitro binding of lymphocytes and monocytes to VCAM-1 on stimulated endothelium.