7092444
CD18 Mouse anti-Human, FITC, Clone: 6.7, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD18
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Target Species
Cynomolgus, Human, Porcine, Rabbit, Rhesus Monkey
Immunogen
Cloned Human DS6 TCR γδ+ Cells
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
6.7
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
ITGB2; Integrin beta-2; Beta subunit for LFA-1, MAC-1/CR3, and p150,95
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Description
- The 6.7 monoclonal antibody specifically binds to β2 integrin, a 90-95 kDa transmembrane protein, which associates non-covalently as a heterodimer with the a chains of CD11a, CD11b, or CD11c
- CD18 is expressed on lymphocytes, monocytes, and more weakly on granulocytes
- LFA-1 has been shown to play an important role in homotypic and heterotypic cellular adhesion in immune and inflammatory responses
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.