7092507
CD27 Mouse anti-Human, V500, Clone: M-T271, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD27
Applications
Flow Cytometry
Conjugate
Violet Fluor 500 (V500)
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing protein stabilizer, glycerol and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Clone
M-T271
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human T-CLL cells
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The M-T271 monoclonal antibody specifically binds to CD27
- CD27 presents asa type I transmembrane, disulphide-linked 110 kDa homodimer comprised of two polypeptide chains
- The CD27 molecule is a lymphocyte-specific member of the TNF/NGF-R family, and is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes, activated B cells and NK cells
- CD27 is highly induced on T cells after TCR stimulation
- CD27 binds to CD70 (also known as, CD27 ligand or CD27L) and may be involved in cellular interaction of T and B lymphocytes
- The antibody is conjugated to BD Horizon™ V500, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the Violet laser with an Ex max of 415nm and Em Max at 500 nm
- BD Horizon V500 conjugates emit at a similar wavelength to Amcyan yet exhibit reduced spillover into the FITC channel
- For more information on BD Horizon V500, visit bdbiosciences.com/colors.