7092578
CD43 Mouse anti-Human, FITC, Clone: 1G10, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD43
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
1G10
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
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Description
- The 1G10 monoclonal antibody specifically binds to CD43, a 95-135 kDa sialoglycoprotein that is highly expressed on most human leucocytes
- CD43 is encoded by the SPN gene and is also known as Sialophorin, Galactoglycoprotein (GALGP), Leukosialin, and Leukocyte sialoglycoprotein
- The CD43 antigen is expressed on T cells, pre-B cells and activated B cells, NK cells and granulocytes, but is not present on resting peripheral blood B cells, red blood cells, platelets and non-hematopoietic cells
- CD43 is enzymatically shed from leucocytesurfaces following activation by various stimuli
- CD43 appears to be involved in intercellular interactions that regulate T, B, and NK cell functions
- This antibody is suitable for staining formalin-fixed, paraffin-embedded tissue sections with TUF pretreatment.