7092638

CD55 Mouse anti-Human, FITC, Clone: IA10, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD55

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

IA10

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

DAF

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Description

  • Reacts with CD55, decay-accelerating factor (DAF), a glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein of approximately 70 kDa, expressed on hematopoietic cells
  • It has been suggested that the role of DAF is to protect cells from damage by autologous complement preventingthe amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertases, C4b2a3b and C3bBb3b
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.