7092658

CD63 Mouse anti-Human, FITC, Clone: H5C6, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD63

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

H5C6

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human Splenic Adherent Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The H5C6 monoclonal antibody reacts with CD63
  • CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages
  • This molecule is also referred to in the literature as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 superfamily (TM4SF)
  • It is widely expressed on surface and in the cytoplasm of various hematopoietic (monocytes, macrophages) and non-hematopoietic cells (endothelium, fibroblasts, osteoclasts, smooth muscle)
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.