Ornithine Decarboxylase Mouse, Clone: SPM565, Novus Biologicals™

Ornithine Decarboxylase

Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Monoclonal

Purified

RUO

Human, Rat

P11926

4953

Recombinant human ODC-1 protein

Primary

Store at 4C.

53 kDa

SPM565

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Unconjugated

Mouse

Cell Cycle and Replication

PBS with 0.05% BSA. with 0.05% Sodium Azide

ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1

ODC1

IgG1 κ

Protein A purified

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.