Pax7 Antibody (SPM613) - Azide and BSA Free, Novus Biologicals™

Pax7

1.0 mg/mL

Immunohistochemistry (Paraffin)

Unconjugated

Mouse

Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

PBS with No Preservative

5081

Recombinant fragment (aa300-600) of human PAX7 protein

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

57 kDa

SPM613

Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml

Monoclonal

Purified

RUO

Human

FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

PAX7

IgG1 κ

Protein A or G purified

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).