Moesin Mouse anti-Human, Rat, Clone: MSN/491, Novus Biologicals™

Moesin

Western Blot 0.5-1ug/ml, Simple Western 1.0 ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page

Monoclonal

Purified

RUO

Human, Rat

P26038

4478

Recombinant human Moesin protein

Primary

Store at 4C.

MSN/491

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation

Unconjugated

Mouse

Cytoskeleton Markers, Stem Cell Markers

PBS with 0.05% BSA. with 0.05% Sodium Azide

Membrane-organizing extension spike protein, moesin

MSN

IgG1 κ

Protein A purified

Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.