7143926
53BP1 Recombinant Rabbit Monoclonal Antibody (BL-250-1H11), Bethyl Laboratories
Rabbit Recombit Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
53BP1
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q12888
Gene ID (Entrez)
7158
Immunogen
Between 350 and 400
Primary or Secondary
Primary
Content And Storage
4° C
Gene
TP53BP1
Clone
BL-250-1H11
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias
TP53BP1, p202
Gene Symbols
TP53BP1
Isotype
IgG
Purification Method
Purified
Product Type
Antibody
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- 53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase
- Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks
- 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.