7143992
MCM6 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MCM6
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
MCG40308, Mis5, P105MCM
Immunogen
Between 775 and C-term
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MCM6
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P97311, Q14566
Gene ID (Entrez)
17219, 4175
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Guinea pig_10141, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and No The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication
- The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins
- The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme
- The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.