7144158
PC4 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PC4
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
PC4, TIS7
Immunogen
Between 77 and 127
Primary or Secondary
Primary
Content And Storage
4° C
Gene
SUB1
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P11031, P53999
Gene ID (Entrez)
10923, 20024
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity
- The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH
- TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.