7144159
CDC20 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CDC20
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
bA276H19.3, CDC20 (cell division cycle 20, S. cerevisiae, homolog), CDC20 cell division cycle 20 homolog, CDC20 cell division cycle 20 homolog (S. cerevisiae), CDC20A, cell division cycle 20 homolog, cell division cycle 20 homolog (S. cerevisiae), p55CDC
Immunogen
Between 50 and 100
Primary or Secondary
Primary
Content And Storage
4° C
Gene
CDC20
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
Q12834, Q9JJ66
Gene ID (Entrez)
107995, 991
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Small-ea Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex
- Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates
- The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons
- CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.