7144203
PARP1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PARP1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
PARP
Gene Symbols
PARP1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunofluorescence, Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P09874
Gene ID (Entrez)
142
Immunogen
Between 50 and 100
Primary or Secondary
Primary
Content And Storage
4° C
Gene
PARP1
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, Orangutan, Monkey, Gorilla, Chimpanzee, Ferret and Crab-eating macaque Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors
- Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein
- Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.