7144183

NBS1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

NBS1

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95

Gene Symbols

NBN

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunofluorescence, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

O60934

Gene ID (Entrez)

4683

Immunogen

Between 704 and 754

Primary or Secondary

Primary

Content And Storage

4° C

Gene

NBN

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Francois's leaf monkey and The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex
  • This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.