7144296

NELFA Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

NELFA

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

FLJ10442, FLJ25112, NELF-A, NELFA, P/OKcl.15

Gene Symbols

NELFA

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9H3P2

Gene ID (Entrez)

7469

Immunogen

Between 499 and 549

Primary or Secondary

Primary

Content And Storage

4° C

Gene

NELFA

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Guinea pig_10141, Orangutan, Monkey, Gorilla, Chimpanzee, hirteen-lined ground This gene is expressed ubiquitously with higher levels in fetal than in adult tissues
  • It encodes a protein sharing 93% sequence identity with the mouse protein
  • Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4
  • This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome
  • The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients
  • This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.