7144503
MEK1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MEK1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
MAPKK1, MEK1, MKK1, PRKMK1
Gene Symbols
MAP2K1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q02750
Gene ID (Entrez)
5604
Immunogen
Between 343 and 393
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MAP2K1
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with X
- laevis, X
- tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Pig, Panda, Monkey, Gorill MAP2K1 (MEK1) is a dual specificity mitogen-activated protein kinase (MAPK) kinase
- It is an essential component of the MAP kinase pathway and stimulates the enzymatic activity of MAP kinases in response to various signals
- Growth factors, cytokines, and proto-oncogenes transduce their signals through the activation of RAS, which leads to activation of the serine/threonine kinase RAF, and then to activation of MAPK kinase
- MAP2K1 is activated by the Raf family member p74raf-1, through phosphorylation of serine residues at positions 217 and 221 in the activation loop.