7144415
ANKRD28/PITK Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
ANKRD28/PITK
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
KIAA0379
Gene Symbols
ANKRD28
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O15084
Gene ID (Entrez)
23243
Immunogen
Between 975 and 1025
Primary or Secondary
Primary
Content And Storage
4° C
Gene
ANKRD28
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Horse, Rabbit, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Naked mole rat an Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates
- Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha
- Selectively inhibits the phosphatase activity of PPP1C
- Targets PPP1C to modulate HNRPK phosphorylation
- ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.