7163727
CD138 (Syndecan-1) Monoclonal Antibody (MI15), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD138 (Syndecan-1)
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias
AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
Gene Symbols
Sdc1
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Clone
MI15
Applications
Flow Cytometry
Conjugate
PerCP-eFluor 710
Host Species
Mouse
Target Species
Human
Gene Accession No.
P18827
Gene ID (Entrez)
6382
Immunogen
U-266 cell line
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Sdc1
Related Products
Description
- Description: This MI15 monoclonal antibody reacts with human CD138, also known as syndecan-1
- CD138 is a transmembrane protein containing chondroitin sulfate and heparin sulfate moieties responsible for binding to the extracellular matrix components
- CD138 is not expressed by mature B cells but is present on pre-B cells and the finally differentiated plasma cells
- Applications Reported: This MI15 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This MI15 antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- PerCP-eFluor 710 emits at 710 nm and is excited with the blue laser (488 nm); it can be used in place of PerCP-Cyanine5.5
- We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative
- Please make sure that your instrument is capable of detecting this fluorochrome
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes
- CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury
- It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells
- Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics
- Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.