7188375

Histone H4K20me1 Monoclonal Antibody (5E10-D8), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H4K20me1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

BcDNA:RH52884; CELE_T10C6.11; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; F07B7.11; F07B7.4; F45F2.12; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4C3; H4c4; H4C5; H4C6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4K20me; H4Lys20me; H4Lys20me1; H4M; H4r; his-20; his-22; His4; his-4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873;

Gene Symbols

H4-16, H4C1, H4C14, H4C2, H4C5, H4C9

Isotype

IgG1 κ

Purification Method

Protein A

Product Type

Antibody

Clone

5E10-D8

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P62805

Gene ID (Entrez)

121504, 8294, 8359, 8366, 8367, 8370

Immunogen

This Histone H4 monomethyl Lys20 was raised against a synthetic peptide containing monomethyl Lys20 of Histone H4.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

H4C1

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Description

  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
  • Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes
  • The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures
  • This gene is intronless and encodes a member of the histone H4 family
  • Transcripts from this gene lack polyA tails but instead contain a palindromic termination element
  • This gene is found in the large histone gene cluster on chromosome 6.