Suz12 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Suz12
Applications
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
Q15022, Q80U70
Gene ID (Entrez)
23512, 52615
Immunogen
This Suz12 antibody was raised against a peptide corresponding to the C-terminus of human Suz12.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
SUZ12
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
2610028O16Rik; AI195385; AU016842; AW536442; ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; KIAA0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit
Gene Symbols
SUZ12
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
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Description
- SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma
- Recombination of these breakpoints results in the fusion of this gene and JAZF1
- SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene
- The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.