7188378
OGT/O-GlcNAc transferase Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
OGT/O-GlcNAc transferase
Applications
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Alias
GlcNAc
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen
This antibody was raised against a recombinant protein corresponding to the N-terminal region of human OGT.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Related Products
Description
- O-linked N-acetylglucosamine (O-GlcNAc) is a posttranslational modification characterized by the attachment of N-acetylglucosamine to specific serine or threonine residues
- Unlike other protein glycosylations, O-GlcNAc modifications occur within the nucleus and cytoplasm
- They are found on many cellular proteins, including nuclear pore, oncogene, cytoskeletal, heat shock, viral and transcription regulatory proteins
- O-GlcNAc glycosylations are thought to obscure phosphorylation sites, counteracting phosphorylation-dependent signaling pathways and protein interactions.