KLF4 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
KLF4
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O43474
Gene ID (Entrez)
9314
Immunogen
This kLF4 antibody was raised against recombinant full-length human kLF4.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
KLF4
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
BOS_9305; endothelial Kruppel-like zinc finger protein; Epithelial zinc finger protein EZF; EZF; Gklf; gut Kruppel-like factor; Gut-enriched krueppel-like factor; Klf4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); RP11-150J11.1; Zie
Gene Symbols
KLF4
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans
- It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors
- KLF4 exerts its functional relevance across varied cellular pathways
- As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells
- Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control
- Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.