7188698

Histone H2BK120ub1 Monoclonal Antibody (56), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H2BK120ub1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene ID (Entrez)

255626

Immunogen

This Histone H2B ubiquityl Lys120 antibody was raised against a branched peptide corresponding the the ubiquitin conjugation site at Lys120 of human Histone H2B.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

HIST1H2BA

Clone

56

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q96A08

Gene Symbols

HIST1H2BA

Isotype

IgG2a

Purification Method

Protein G

Product Type

Antibody

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Description

  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
  • Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes
  • The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures
  • This gene encodes a member of the histone H2A family and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.