7188708
PGC1-beta Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PGC1-beta
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q86YN6
Gene Symbols
PPARGC1B
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene ID (Entrez)
133522
Immunogen
This PGC1-beta antibody antibody was raised against a peptide within the N-terminal region of human PGC1-beta.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
PPARGC1B
Related Products
Description
- PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha
- The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner
- Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.