DMAP1 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
DMAP1
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q9NPF5
Gene ID (Entrez)
55929
Immunogen
This antibody was raised against a peptide within the C-terminal region of human DMAP1.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
DMAP1
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
1500016M21Rik; BOS_3636; DKFZp686L09142; Dmap1; Dmtap1; DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1 associated protein 1; DNMT1 associated protein-1; DNMT1-associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425; MAT1-mediated transcriptional repressor; MEAF2; mKIAA1425; Mmtr; RP5-891H21.2; SWC4
Gene Symbols
DMAP1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription
- The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1
- During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication
- The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription
- The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others
- DMAP1 is found in a wide variety of living organisms from yeasts to humans
- The human DMAP1 gene is localized on chromosome 1p34.