7188437

RING1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

RING1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q06587

Gene ID (Entrez)

6015

Immunogen

This antibody was raised against a peptide within the C-terminal region of human RING1.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

RING1

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

E3 ubiquitin-protein ligase RING1; Polycomb complex protein RING1; Really interesting new gene 1 protein; RING finger protein 1; Ring1; Ring1A; RING-type E3 ubiquitin transferase RING1; Rnf1; Transcription repressor Ring1A

Gene Symbols

RING1

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Description This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain
  • The gene product can bind DNA and can act as a transcriptional repressor
  • It is associated with the multimeric polycomb group protein complex
  • The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains
  • It interacts with the CBX4 protein via its glycine-rich C-terminal domain
  • The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.