7188843

Phospho-CENP-A (Ser18) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-CENP-A (Ser18)

Applications

Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P49450

Gene ID (Entrez)

1058

Immunogen

This antibody was raised against a synthetic peptide containing phosphorylated serine 16 and 18 of human CENP-A.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Cenpa

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; Centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; Histone H3-like centromeric protein A; RGD1563607

Gene Symbols

Cenpa

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes
  • CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere
  • CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.