Dab1 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Dab1
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Mouse
Gene Accession No.
P97318
Gene ID (Entrez)
13131
Immunogen
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of murine Dab1 at amino acids 400-555.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
DAB1
Concentration
75 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
AI956902; C630028C02Rik; Dab reelin signal transducer 1; Dab, reelin signal transducer, homolog 1; Dab, reelin signal transducer, homolog 1 (Drosophila); DAB1; DAB1, reelin adaptor protein; disabled 1; Disabled homolog 1; RP23-356E21.1; scm; scr; scrambler; yot; yotari
Gene Symbols
DAB1
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is directed against Dab1 from mouse
- Cross-reactivity with other species has not been determined
- No reaction occurs with human or mouse Dab2
- The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function
- In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer
- This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain
- Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.