Zic-1 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Zic-1
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P46684, Q15915
Gene ID (Entrez)
22771, 7545
Immunogen
The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with an 18 aa synthetic peptide from a region near the N-Terminus of mouse Zic-1. This domain is completely conserved in human ZIC-1.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
ZIC1
Concentration
1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
CRS6; odd-paired homolog; ZIC; Zic family member 1; Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; ZIC1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1; ZNF201
Gene Symbols
ZIC1
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This is an IgG preparation of whole rabbit antiserum purified by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- This antibody is directed against Zic-1 from mouse
- In general, this antibody also detects human Zic-1
- Cross-reactivity with other species is likely but has not been determined
- This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins
- Members of this family are important during development
- Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor
- This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3
- This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.