72-005-6

ATG3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 72-005-6-Each-of-1 In Stock ₹ 53,044.00

72-005-6 - Each of 1

₹ 53,044.00

In Stock

Quantity

1

Base Price: ₹ 53,044.00

GST (18%): ₹ 9,547.92

Total Price: ₹ 62,591.92

Antigen

ATG3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATG3

Gene Alias

2610016C12Rik; APG3; Apg3l; APG3-like; Apg3p; atg3; ATG3 autophagy related 3 homolog; atg3.S; Atg3l; autophagy related 3; autophagy related 3 S homeolog; autophagy-related 3; autophagy-related protein 3; DKFZp564M1178; EGK_11288; FLJ22125; hApg3; MGC15201; PC3-96; Pig1; PIG-1; preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3; XELAEV_18014721mg

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64422, 67841

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9CPX6, Q9NT62

Gene Symbols

ATG3

Immunogen

Recombinant protein corresponding to Human ATG3 (aa 63-254)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
  • The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
  • The purified antibody is tested for its functionality in various relevant research applications
  • The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
  • ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1
  • ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.