72-040-5

MKP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 72-040-5-Each-of-1 In Stock ₹ 44,500.00

72-040-5 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

MKP3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DUSP6

Gene Alias

1300019I03Rik; dual specificity phosphatase 6; dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; Dusp6; DUSP6-ALT; HH19; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; Mkp3; MKP-3; PYST1; serine/threonine specific protein phosphatase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1848

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q16828

Gene Symbols

DUSP6

Immunogen

Peptides corresponding to human MKP3 [1) aa71-aa89 2) aa178-aa195]

Quantity

100μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with Monkey, Dog, Bovine, Horse
  • DUSP6 is a member of the dual specificity protein phosphatase subfamily
  • These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
  • They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation
  • Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
  • This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm
  • Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.