MKP3 Recombinant Rabbit Monoclonal Antibody (ARC0237), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535048-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA535048 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
MKP3
Classification
Monoclonal
Concentration
2.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q16828, Q64346, Q9DBB1
Gene Symbols
DUSP6
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 282-381 of human DUSP6 (Q16828)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
ARC0237
Conjugate
Unconjugated
Gene
DUSP6
Gene Alias
1300019I03Rik; dual specificity phosphatase 6; dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; Dusp6; DUSP6-ALT; HH19; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; Mkp3; MKP-3; PYST1; serine/threonine specific protein phosphatase
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116663, 1848, 67603
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: ARGKNCGVLV HCLAGISRSV TVTVAYLMQK LNLSMNDAYD IVKMKKSNIS PNFNFMGQLL DFERTLGLSS PCDNRVPAQQ LYFTTPSNQN VYQVDSLQST DUSP6 is a member of the dual specificity protein phosphatase subfamily
- These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
- They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation
- Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
- This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm
- Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.