7215106

Phospho-MCM2 (Ser139) Recombinant Rabbit Monoclonal Antibody (MCM2S139-B12), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-MCM2 (Ser139)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias

AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; Kiaa0030; MCM DNA helicase complex subunit MCM2; Mcm2; Mcmd2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance complex component 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae); Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; MITOTIN; mKIAA0030; Nuclear protein BM28; YBL023C; YBL0438

Gene Symbols

MCM2

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

MCM2S139-B12

Applications

Flow Cytometry, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P49736, P97310

Gene ID (Entrez)

17216, 312538, 4171

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho MCM2.

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

MCM2

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Description

  • Description MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication
  • MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division
  • It is similar to members of the family of early S-phase proteins
  • MCM2 has been mapped to 3q21
  • From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).