7215204

Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-MARCKS (Ser167, Ser170)

Applications

Flow Cytometry

Conjugate

FITC

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P26645, P29966, P30009

Gene ID (Entrez)

17118, 25603, 4082

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.

Primary or Secondary

Primary

Content And Storage

4° C, store in dark

Gene

MARCKS

Clone

MARCKSS167170-C9

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain

Gene Symbols

MARCKS

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • MARCKS is a substrate for protein kinase C
  • It is localized to the plasma membrane and is an actin filament crosslinking protein
  • Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm
  • The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.