7218622
SOX11 Monoclonal Antibody (SOX11-C1), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
SOX11
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox11; Sox-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-box transcription factor 11; SRY-related HMG-box gene 11; transcription factor SOX-11
Gene Symbols
SOX11
Primary or Secondary
Primary
Content And Storage
4° C
Gene
SOX11
Clone
SOX11-C1
Applications
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P35716
Gene ID (Entrez)
6664
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description The MAb SOX11-C1 (C1) recognizes human Sox11
- The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins
- Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4
- Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells
- Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes
- Sox11 is also expressed in epithelial ovarian cancer and gliomas
- This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate
- The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins
- The protein may function in the developing nervous system and play a role in tumorigenesis.