7226339

HPR Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

HPR

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Rat

Gene Accession No.

P00739

Gene ID (Entrez)

3250

Immunogen

Gln102-Glu347 (Accession P00739), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

HPR

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

A-259H10.2; Haptoglobin-related locus; haptoglobin-related protein; HP; HPR

Gene Symbols

HPR

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Description This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin
  • Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor
  • This protein may also be a clinically important predictor of recurrence of breast cancer.