DUSP5 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
DUSP5
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q16690
Gene ID (Entrez)
1847
Immunogen
Met1-Glu135 (Accession Q16690), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
DUSP5
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
candidate plasticity-related gene 21; Cpg21; dual specificity phosphatase 5; dual specificity protein phosphatase 5; dual specificity protein phosphatase 5-like; dual specificity protein phosphatase hVH3; DUSP; DUSP5; Gm337; HVH3; LOW QUALITY PROTEIN: dual specificity protein phosphatase 5; MAP-kinase phosphatase (cpg21); MAP-kinase phosphatase CPG21; serine/threonine specific protein phosphatase; VH1-like phosphatase 3; VH3
Gene Symbols
DUSP5
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
- These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
- They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation
- Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
- This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.