CD1d Monoclonal Antibody (1B1), Brilliant Violet™ 480, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD1d
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
AI747460; Antigen-presenting glycoprotein CD1d; antigen-presenting glycoprotein CD1d1; Cd1; CD1.1; CD1A; Cd1d; CD1D antigen; CD1D antigen, d polypeptide; CD1d molecule; CD1d.1; Cd1d1; CD1d1 antigen; CD1d1 molecule; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; Ly-38; R3; R3G1; T-cell surface glycoprotein CD1d; T-cell surface glycoprotein CD1d1; thymocyte antigen CD1D
Gene Symbols
Cd1d1
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Cd1d1
Clone
1B1
Applications
Flow Cytometry
Conjugate
Brilliant Violet 480
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P11609
Gene ID (Entrez)
12479
Isotype
IgG2b κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- CD1d is a heavy chain associated with Beta 2 microglobulin on cortical thymocytes
- Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells
- CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins
- The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
- The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
- The human genome contains five CD1 family genes organized in a cluster on chromosome 1
- The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
- The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail
- Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.