7240419
TEM7 Recombinant Rabbit Monoclonal Antibody (104), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TEM7
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
2410003I07Rik; ADP-ribosylation factor-like 12; AI848450; Arl12; DKFZp686F0937; FLJ36270; FLJ45632; plexin domain containing 1; plexin domain-containing protein 1; PLXDC1; TEM3; TEM7; TEM7 related; tumor endothelial marker 3; Tumor endothelial marker 7; tumor endothelial marker7
Gene Symbols
PLXDC1
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
104
Applications
ELISA
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q8IUK5
Gene ID (Entrez)
57125
Immunogen
Recombinant Human TEM7/PLXDC1 protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
PLXDC1
Related Products
Description
- Specificity: Human TEM7/PLXDC1 Recently, using SAGE (Serial Analysis of Gene Expression) technology, St
- Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium
- Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9)
- TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain
- TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis
- The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis
- Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.