7240414

CD105 Recombinant Rabbit Monoclonal Antibody (029), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD105

Concentration

1 mg/mL

Classification

Recombinant Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Gene Symbols

ENG

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

Clone

029

Applications

ELISA

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Mouse

Gene Accession No.

Q63961

Gene ID (Entrez)

13805

Immunogen

Recombinant Mouse Endoglin/CD105 Protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

ENG

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Description

  • Specificity: Mouse Endoglin/CD105 CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells
  • It exists on an O- and N-glycosylated homodimer
  • Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker
  • CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.