7240421
Growth Hormone Recombinant Rabbit Monoclonal Antibody (177), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Growth Hormone
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; RNGHGP; Somatotropin
Gene Symbols
Gh1
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
177
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P01241
Gene ID (Entrez)
2688
Immunogen
Recombinant Human Growth Hormone/GH1 Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
Gh1
Related Products
Description
- Specificity: Human Growth Hormone/GH1 Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control
- The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17
- The five genes share a remarkably high degree of sequence identity
- Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa
- HGH is produced by the somatotroph cells in the pituitary
- It acts through binding to membrane receptors that belong to the cytokine receptor subfamily
- Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1
- It stimulates both the differentiation and proliferation of myoblasts
- It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
- Mutations or deletions in the gene lead to growth hormone deficiency and short stature.