7240432
Growth Hormone Monoclonal Antibody (09), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Growth Hormone
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; RNGHGP; Somatotropin
Gene Symbols
Gh1
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Clone
09
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P01241
Gene ID (Entrez)
2688
Immunogen
Recombinant Human Growth Hormone Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
Gh1
Related Products
Description
- Specificity: Human Growth Hormone Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control
- The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17
- The five genes share a remarkably high degree of sequence identity
- Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa
- HGH is produced by the somatotroph cells in the pituitary
- It acts through binding to membrane receptors that belong to the cytokine receptor subfamily
- Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1
- It stimulates both the differentiation and proliferation of myoblasts
- It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
- Mutations or deletions in the gene lead to growth hormone deficiency and short stature.