7240477
PTX3 Monoclonal Antibody (03), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PTX3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
Gene Symbols
PTX3
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Clone
03
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P26022
Gene ID (Entrez)
5806
Immunogen
Recombinant Human PTX3/Pentraxin 3/TSG-14 Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
PTX3
Related Products
Description
- Specificity: Human PTX3/Pentraxin 3/TSG-14 Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure
- Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents
- Ptx3 belongs to the family of "elong pentraxins"e, which have C-terminal pentraxin domains and novel amino-terminal domains
- Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium
- It is synthesized in IgA glomerulonephritis and activates mesangial cells
- Secretion of Ptx3 in adipose cells can be induced by TNF
- Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity
- The human PTX3 gene maps to chromosome 3q25.