7240479
CD205 Recombinant Rabbit Monoclonal Antibody (019), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD205
Concentration
1 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Gene Symbols
LY75
Isotype
IgG
Purification Method
Protein A
Product Type
Antibody
Clone
019
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Mouse
Gene Accession No.
Q60767
Gene ID (Entrez)
17076
Immunogen
A synthetic peptide corresponding to the N-terminus of the Mouse DEC-205/LY75
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
LY75
Related Products
Description
- Specificity: Mouse DEC-205/LY75 CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity
- CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells
- CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region
- Further, CD205 also prompts the reduced proliferation of B lymphocytes
- Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.