7240521
MICB Monoclonal Antibody (04), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MICB
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MHC class I-like located near the LRC, 2; MHC class I-like molecule PERB11.2-IMX; MHC I like leukocyte 2; MICB; MIC-B; Mill2; Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1; PERB11.2; sMICB; soluble MICB; stress inducible class I homolog
Gene Symbols
MICB
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Clone
04
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q29980
Gene ID (Entrez)
4277
Immunogen
Recombinant Human MICB Protein.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
MICB
Related Products
Description
- Specificity: Human MICB MICB encodes the highly polymorphic MHC (HLA) class I chain-related gene B
- The protein product is expressed on the cell surface
- It is thought that MICB functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells
- MICB is broadly recognized by NK cells and T cells with NKG2D receptor on their surface
- The complex NKG2D-MICB results in MICB expressing cytolytic T cells and NK cells against epithelial tumor cells.