7240918
OLFM3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
OLFM3
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q96PB7
Gene ID (Entrez)
118427
Immunogen
Gln24-Glu198 (Accession Q96PB7), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
Olfm3
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
B230206G02Rik; NOE3; NOELIN3; Noelin-3; olfactomedin 3; olfactomedin related ER localized protein 3; olfactomedin-3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
Gene Symbols
Olfm3
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin
- Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure
- OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins
- OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue
- Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.