7240949

BMP-7 Monoclonal Antibody (C5), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

BMP-7

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5

Gene Symbols

Bmp7

Isotype

IgG2b κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C5

Applications

Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P18075

Gene ID (Entrez)

655

Immunogen

Asp30-His431 (Accession P18075), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

Bmp7

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Description

  • The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth
  • Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily
  • BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site
  • Based on its expression early in embryogenesis, BMP7 has a proposed role in early development
  • In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.